Science / Health

The Importance Of Finding A Reliable Source For Immunoassay Reagents

When you are looking into research and diagnostic applications you need a broad range of immunoassay reagents.  The company should produce their reagents the same way each and every time.  Proper reagents and controls are critical.  You need to find a company that you can depend on for all of your immunoassay reagents.  This means that they have proper quality control in place that will produce reagents that are exactly the same over and over again.  They should be robust and sustainable.

One such company is https://shop.surmodics.com/immunoassay-reagents/

These reagents are signal generating labels, antibodies, and separation matrices.  The key to the reagents is the antibodies.  The very success of any immunoassay is dependent on it.  This means that it is very important to have the right reagents for particular immunoassay testing.  There are two types of antibodies: the monoclonal and polyclonal. 

When we have a reaction between the antibody and antigen then you are performing Immunoassay testing.  An immune complex is formed when the antibody immunoanalytical reagents are incubated after mixing. 

Testing for small molecules

When you mix an antibody and antigen it will allow for testing of the solution and determine what small molecules might be in there.  This small molecule could be a variety of things.  Quite often this small molecule is a protein.  However, it could be urine, serum, or other bodily fluids.  This test is a biochemical test. 

Oftentimes a caliber is used during testing.  This is where the known miniature molecule in question is present.  This allows for detailed accuracy to ensure that the test results are accurate.  However, if you don’t have a reliable source for your Immunoassay reagents this process could be very inaccurate.  You need to ensure your reagents are doing what they are intended to do.  Testing a sample of something that is known is a very good way to test your reagent as well.  Compare your testing sample to the actual sample of which you know that a particular molecule is in.  This is what they call a calibrator. 

Most Immunoassays require a chemical bond with an antigen and an antibody with some kind of detectable label.  These detectable labels give off a certain look.  This look could be something as simple as a glow under black light.  Other ways that the label will show itself either by changing the color of the solution or can be induced to emit light.

The immunoassay reagents

Immunoassays have been around since the 1950s.   Solomon Berson and Rosaly Sussman Yalow are responsible for discovering this type of testing and Yallow even won a Nobel Prize for it in the late 1970s.   This type of testing got far more accurate in the 1960s as they fine-tuned it.  This type of testing is used in millions of labs found across the globe.  This was a huge breakthrough for modern medicine and even used for criminal justice.  It is used to measure a wide range of pathogens, proteins and other blood sample molecules.  When performing these important tests you will want to ensure the immunoassay reagents are controlled and accurate.

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